Secondary manic or hypomanic states are associated with several conditions. Common post - traumatic brain injury psychiatric comorbidities include affective, behavioral and cognitive disorders. While bipolar disorder is not as common as other mood disorders or anxiety disorders after traumatic brain injury, it is nevertheless a potential psychiatric complication of traumatic brain injury. In this article we present a case that has been reported psychiatric conditions changing after a traumatic brain injury. We recommend taking attention to those possible causes of changed psychiatric conditions after traumatic brain injury, and the association between comorbid diseases and the diagnostic difficulties